Analysis of glial secretome in MeCP2-pathies

Reference: Laurent Villard Abstract: n.a PROJECT DETAILS  beginning: 2013. end: 2015. Country of research: France Counry of funding source: France Funding organization: French Association Rett Syndrome Financing: PRIVATE FUNDERS – 29 500 € hyperlink

Investigation of the Importance of a hitherto Uncharacterized Mecp2-Isoform for Neuronal Morphogenesis and Chromatin related functions

Reference: Charlotte Kilstrup-Nielsen Abstract: MeCP2 is a protein that has been found to bind and probably regulate important aspects of chromatin but it is still not clear how defects in MeCP2 cause the neurologic problems of RTT. It has become clear that MeCP2 gets phosphorylated in neurons that are activated by external stimuli but we … Read more

Understanding and rescuing respiratory arrhythmias in a mouse model of Rett Syndrome

Reference: Ana Abdala Sheikh Abstract: Breathing is the most important process controlled by the brain; it is a rhythm that happens non-stop from birth until death. It constantly changes to allow for other behaviors such as speech, singing, exercising, eating, drinking, coughing. Frequent periods of breath holding are a very common feature of Rett syndrome. … Read more

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