Reference: 57000005 Abstract: This is a summary of the request. The Governor Kremers Centre (GKC) started in 2002 as a corporate initiative of service providers and the academic chair on intellectual disability at Maastricht University. It is now aiming at extending and consolidating its activities as a consortium of Maastricht University, major service providers and … Read more
Reference: na Abstract: n.a PROJECT DETAILS beginning: 2012. end: 2014. Country of research: Italy Counry of funding source: Italy Funding organization: Ministry of Health Financing: NATIONAL FUNDINGS – 284 440 € hyperlink
Reference: 73430 Abstract: The study design is the natural extension of our previous research works that had already been supported (www.humangenom.hu, www.eurosca.org). It is clear nowadays, that the functions of the carnitine are not restricted to the role of the oxidation of the long-chain fatty acids. The main direction of the planned research is the … Read more
Reference: ANRn.a.8-MNPSn.a.007 Abstract: Psychotic disorders (schizophrenia, bipolar disorder, pervasive developmental disorders) are disabling disorders of variable clinical expression ?, ?d resulting interaction between genetic and environmental factors during critical periods of brain development. Some candidate genes have been identified . Among them, neuregulin, RGS4, DISC1, reelin, BDNF and glutamatergic receptors are involved in the formation … Read more
Reference: B03 – Subproject to SFB 992: Medical Epigenetics (MEDEP) From basic mechanisms to clinical applications Abstract: The methyl-CpG-binding protein 2 (MeCP2) detects symmetrically methylated cytosine-guanine sequences (CpG) in the genomic DNA and modulate gene expression by recruiting coactivator and corepressor-proteins.ﾠWe found that MeCP2 is significantly downregulated in hypertrophic and failing heart.ﾠThe functional significance of … Read more
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