Rett syndrome: hopes of gene therapy

Reference: SP4443, GN1755 Abstract: For many years, Rett syndrome was widely regarded as an incurable disorder, as it was generally thought to cause irreversible changes in the brain. Then, in 2007, came the astonishing discovery that it was possible to reverse the symptoms of Rett syndrome in a laboratory model of the disorder, using a … Read more

Pharmacological treatment of respiratory disorders in a mouse model of Rett syndrome

Reference: Paton, Julian Abstract: Breathing abnormalities consisting of rapid deep respiration followed by cessation of breathing and an irregular interval between breaths are a common and distressing feature of Rett syndrome (RTT). Using a mouse model we have shown that injections of a compound that boosts the brain concentration of the inhibitory neurotransmitter ? amino-butyric … Read more

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Reference: Nicoletta Landsberger Abstract: n.a PROJECT DETAILS  beginning: 2012. end: 2012. Country of research: Italy Counry of funding source: Italy Funding organization: Associazione Italiana per la Ricerca sul Cancro, AIRC Investigator Grant Financing: PRIVATE FUNDERS – 40 000 € hyperlink

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