The contribution of histone deacetylases to the emergence of rett syndrome investigated by in vitro and in vivo mouse model systems

Reference: Lagger, Sabine Abstract: n.a PROJECT DETAILS  beginning: 2011. end: 2013. Country of research: United Kingdom Counry of funding source: Germany Funding organization: EMBO Long Term fellowship Financing: PRIVATE FUNDERS – 34 079 € hyperlink

Pharmacological approaches to restore bdnf levels in cellular and animal models of the Rett syndrome

Reference: GGP08258 Abstract: Rett syndrome (RTT) is the major cause of mental retardation in female children. This pathology is caused by mutations affecting the MECP2 gene located on chromosome X, that in normal conditions regulates the expression of numerous genes. Recently, it has been found that BDNF is one of the target genes of MeCP2 … Read more

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