2008.

Relationships between ghrelin concentration in blood and growth and physical activity in children

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Reference: ETF6225ﾠ Abstract: The biochemical markers that influence the growth of children have not been investigated much. The main goal of the present study is to investigate the relationships between novel peptide hormone ghrelin and anthropometrical characteristics, body composition, physical activity and aerobic working capacity, also to examine the adaptation to aerobic work and weight … Read more

Modeling of pathogenic breathing pattern dysregulation in cardiopulmonary disease

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Reference: 5R33HL087347 Abstract: Ventilatory arrhythmia plays a pathogenic role in many common respiratory disorders ranging from sleep apnea, and acute lung injury to ventilatory support in the setting of chronic lung disease. Brainstem neural circuits that control cardiopulmonary functions generate oscillatory patterns that drive respiratory as well as sympathetic motor activities. These patterns exhibit highly … Read more

Multiannual Programme for Research on Rare Diseases (MRAR) (MRAR) 2006 projectﾠRett therapy -Therapeutic approaches of Rett syndrome: development of human cell models and high-throughput screening of chemical molecules in order to identify new subtsances likely to induce readthrough of a stop codon

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Reference: ANRn.a.6-MRARn.a.003 Abstract: Rett syndrome (RTT) is a neurodevelopmentale dominant X-linked disease affecting almost exclusively girls.ﾠSignificant progress was the discovery of mutations in the MECP2 gene in over 90% of RTT patients.ﾠIn recent years, we have developed a French consortium and determined the spectrum of mutations MECP2.ﾠWe have shown that the four most common MECP2 … Read more

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