Reference: Orphan 0108 Abstract: n.a PROJECT DETAILS beginning: 2008. end: 2010. Country of research: Italy Counry of funding source: Italy Funding organization: Toscana Life Sciences Siena, Italia Financing: PRIVATE FUNDERS – 0 € hyperlink
Reference: GGP05236 Abstract: Rett syndrome is a major cause of mental retardation, second only to the incidence of Down syndrome, and occurs almost exclusively in females. This disease manifests itself after a period of apparently normal development and causes growth retardation, severe psychomotor and autistic-like behaviors . The majority of cases of Rett syndrome is … Read more
Reference: na Abstract: n.a PROJECT DETAILS beginning: 2008. end: 2010. Country of research: Italy Counry of funding source: Italy Funding organization: Fondazione Monte dei Paschi di Siena, Siena, Italia Financing: PRIVATE FUNDERS – 0 € hyperlink
Reference: GGP08258 Abstract: Rett syndrome (RTT) is the major cause of mental retardation in female children. This pathology is caused by mutations affecting the MECP2 gene located on chromosome X, that in normal conditions regulates the expression of numerous genes. Recently, it has been found that BDNF is one of the target genes of MeCP2 … Read more
Reference: GTF05005 Abstract: Mental retardation (MR) is the most frequent cause of serious handicap in humans and an important health-care problem throughout the world. It is estimated to occur in about 1-3% of the general population. It is calculated that X-linked mental retardation (XLMR) may account for about 20ﾖ25% of mentally retarded males. The number … Read more
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