A ChIP-on-chip system for dissecting genetic pathways involved in developmental language disorders

Reference: Fisher Simon Abstract: The Fisher lab has previously reported that mutations of a gene, called FOXP2, cause a severe developmental communication disorder. FOXP2 abnormalities lead to problems with articulating speech, accompanied by impairment in many aspects of language ability. The protein made by FOXP2 controls the behavior of cells by binding to DNA and … Read more

Neurobiology of Rett’s syndrome: cellular etiology and experimental therapeutic strategies in an animal model

Reference: GGP05236 Abstract: Rett syndrome is a major cause of mental retardation, second only to the incidence of Down syndrome, and occurs almost exclusively in females. This disease manifests itself after a period of apparently normal development and causes growth retardation, severe psychomotor and autistic-like behaviors . The majority of cases of Rett syndrome is … Read more

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