Immunomodulatory role of MeCP2 and Rett syndrome.

Reference: Miralv?s Julie Abstract: Rett syndrome is a severe progressive neurodevelopmental disorder caused by dominant mutations in the MECP2 gene. The MeCP2 protein, highly expressed in mature neurons, is a transcriptional repressor of the family of Methyl-CpG-binding proteins (MBP) characterized by their ability to bind to methylated CpG nucleotides. Although the molecular mechanisms responsible for … Read more

Rett Disorder: The pre-regression period

Reference: 325 Franz-Lanyar-Stiftung Abstract: n.a PROJECT DETAILS  beginning: 2007. end: 2008. Country of research: Austria Counry of funding source: Austria Funding organization: Franz-Lanyar-Stiftung, Graz, Austria Financing: PRIVATE FUNDERS – 1 200 € hyperlink

Rett Disorder: The Pre-Regression Period

Reference: Individual projects P19581 Abstract: The planned project is a continuation of our previous research on Rett syndrome, which first demonstrated that the development is noticeable in the first 6 months of life, in contrast to the previous doctrine.ᅠThe aim of the new project is the development of children with Rett syndrome from 6ᅠMonth (12 … Read more

Functional characterization of proteins MECP2 and ACSL4 “as part of the project” post-genomic strategies for the study and prevention of X-linked mental retardation

Reference: neri Abstract: n.a PROJECT DETAILS  beginning: 2006. end: 2007. Country of research: Italy Counry of funding source: Italy Funding organization: PRIN projects Ministry of Education, Universities and Research MIUR Financing: NATIONAL FUNDINGS – 51 510 € hyperlink

ANIMAL MODELS OF NEUROPSYCHIATRIC DISORDERS

Reference: 1Z01MH002179-22 Abstract: Relevant to our research interests in animal models of neuropsychiatric diseases, our Laboratory of Behavioral Neuroscience investigates the behavioral phenotypes of transgenic and knockout mice with mutations in genes expressed in brain pathways involved in neuropsychiatric disorders. We developed and refined a multi-tiered strategy for mouse behavioral phenotyping that is widely used … Read more

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