Downstream Effects of MECP1 Mutations in Rett Syndrome and other forms of X-linked mental retardation Studied by cDNA arrays (C 3)

Reference: C3 – Subproject to SFB 577: Molecular Basis of Clinical variability in Mendelian Disorders Abstract: PROJECT DETAILS  beginning: 2001. end: 2004. Country of research: Germany Counry of funding source: Germany Funding organization: GermanᅠResearch Foundation Financing: NATIONAL FUNDINGS – 0 € hyperlink

Developmental Control of Gene Expression

Reference: 864.03.002 Abstract: One of the most profound and intriguing questions in biology concerns the relationship between genetic diversity and the morphology and biology of different species. The key to understanding this relationship will be found in uncovering the contribution of gene family members to the development of organisms. In recent years it has become … Read more

Determination of the kinetic behaviour of methyl-CpG-binding proteins MeCP2 and MBD1 in living cells by applying fluorescence recovery after photobleaching (FRAP)

Reference: Abstract: PROJECT DETAILS  beginning: 2004. end: 2006. Country of research: Germany Counry of funding source: Germany Funding organization: GermanᅠResearch Foundation Financing: NATIONAL FUNDINGS – 0 € hyperlink

Epigenetic Plasticity of the Genome

Reference: 503433 Abstract: In this ‘post-genomic’ era, advances in epigenetic research represent a new frontier that is predicted to yield novel insights for gene regulation, cell differentiation, stem cell plasticity, organismal development, human diseases, cancer, infertility and aging. A central emerging concept proposes that there is an ‘epigenetic code’, which considerably extends the information potential … Read more

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