Replication and translation of epigenetic information

Reference: SPP 1129 Abstract: Methyl-cytosine binding proteins (MeCPs) play a central role in the mediation of epigenetic effects. They bind to methylated sites in the DNA, recruit histone deacetylases (HDACs9 which may then cause chromatin condensation and transcriptional silencing. We have previously studied the dynamics of DNA replication in living mammalian cells using fluorescence labeling … Read more

Relationships between ghrelin concentration in blood and growth and physical activity in children

Reference: ETF6225ᅠ Abstract: The biochemical markers that influence the growth of children have not been investigated much. The main goal of the present study is to investigate the relationships between novel peptide hormone ghrelin and anthropometrical characteristics, body composition, physical activity and aerobic working capacity, also to examine the adaptation to aerobic work and weight … Read more

Regulation of the neurotrophic factor BDNF gene expression in health and nervous system diseases

Reference: ETF8844 Abstract: Neurotrophin brain-derived neurotrophic factor (BDNF) is a growth factor that has important roles in the development and functioning of nervous system by promoting the survival, differentiation and synaptic plasticity of specific neuronal populations. BDNF has received particular interest for its dysregulation in nervous system disorders. Decreases of BDNF and its receptor TrkB … Read more

Promising markers for the first early detection of Rett syndrome

Reference: Abstract: Rett syndrome (RTT) is a genetic disease that affects the little girl from her 6th month, causing disorders of the nervous system.ᅠIf for the moment there is no cure for the disease, early detection is important and can limit neurological damage related symptoms faster.ᅠResearchers at the Institute of Biomolecules Max Mousseron (1) (IBMM … Read more

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