Reference:
Project5
Abstract:
Rett syndrome and its variant “of Hanefeld” are caused by mutations that affect two different genes, respectively MeCP2 and CDKL5. The aim of this project is the systematic analysis of the gene expression profile of neurons lacking MeCP2 or CDKL5. From the comparison of the obtained data we can determine which pathways are common and which diverge, leading, hopefully finally the ability to associate specific symptoms of the syndrome Rett molecular defects in actions brought by medication.
PROJECT DETAILS
beginning: 2010.
end: 2012.
Country of research: Italy
Counry of funding source: Italy
Funding organization: Pro Rett Ricera
Financing: PRIVATE FUNDERS – 80 000 €